Entity Details

Primary name AGO3
Entity type gene
Source Source Link

Details

PrimaryID192669
RefseqGene
SymbolAGO3
Nameargonaute RISC catalytic component 3
Chromosome1
Location1p34.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-04-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAGO3_HUMAN

GO terms

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GOName
GO:0000794 condensed nuclear chromosome
GO:0000932 P-body
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0004521 endoribonuclease activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006402 mRNA catabolic process
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0010501 RNA secondary structure unwinding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016020 membrane
GO:0016442 RISC complex
GO:0030522 intracellular receptor signaling pathway
GO:0031054 pre-miRNA processing
GO:0035194 post-transcriptional gene silencing by RNA
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035198 miRNA binding
GO:0035278 miRNA mediated inhibition of translation
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0045652 regulation of megakaryocyte differentiation
GO:0046872 metal ion binding
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0070578 RISC-loading complex
GO:0072091 regulation of stem cell proliferation
GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA
GO:1901224 positive regulation of NIK/NF-kappaB signaling

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AGO3Xpo1IntAct26673895 details