Entity Details

Primary name MLKL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D2Y4
EntryNameMLKL_MOUSE
FullNameMixed lineage kinase domain-like protein
TaxID10090
Evidenceevidence at protein level
Length472
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesMlkl

GO terms

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GOName
GO:0004706 JUN kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007257 obsolete activation of JUN kinase activity
GO:0019901 protein kinase binding
GO:0030054 cell junction
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
GO:0051607 defense response to virus
GO:0070207 protein homotrimerization
GO:0070266 necroptotic process
GO:0097527 necroptotic signaling pathway
GO:0097528 execution phase of necroptosis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR036537 Adaptor protein Cbl, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions