Entity Details

Primary name EIF4G1
Entity type gene
Source Source Link

Details

PrimaryID1981
RefseqGeneNG_016850
SymbolEIF4G1
Nameeukaryotic translation initiation factor 4 gamma 1
Chromosome3
Location3q27.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-02-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIF4G1_HUMAN

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001662 behavioral fear response
GO:0002191 cap-dependent translational initiation
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005844 polysome
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0008135 translation factor activity, RNA binding
GO:0008190 eukaryotic initiation factor 4E binding
GO:0010494 cytoplasmic stress granule
GO:0010507 negative regulation of autophagy
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0010942 positive regulation of cell death
GO:0016020 membrane
GO:0016032 viral process
GO:0016281 eukaryotic translation initiation factor 4F complex
GO:0030307 positive regulation of cell growth
GO:0031369 translation initiation factor binding
GO:0031669 cellular response to nutrient levels
GO:0032270 positive regulation of cellular protein metabolic process
GO:0032502 developmental process
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034645 cellular macromolecule biosynthetic process
GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress
GO:0042802 identical protein binding
GO:0043488 regulation of mRNA stability
GO:0045666 positive regulation of neuron differentiation
GO:0060090 molecular adaptor activity
GO:0060964 regulation of gene silencing by miRNA
GO:0080135 regulation of cellular response to stress
GO:0097009 energy homeostasis
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1901215 negative regulation of neuron death
GO:1905537 positive regulation of eukaryotic translation initiation factor 4F complex assembly
GO:1905606 regulation of presynapse assembly
GO:1905612 positive regulation of mRNA cap binding
GO:1905618 positive regulation of miRNA mediated inhibition of translation
GO:1905696 regulation of polysome binding

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
EIF4G1Eif4e2IntAct15153109 details
EIF4G1Eif4eBioGRID12149653 details
EIF4G1Eif3aBioGRID, IntAct20360068 26496610 details
EIF4G1Gspt1BioGRID, IntAct26496610 details
EIF4G1Taok2BioGRID, IntAct26496610 details
EIF4G1Eif3eBioGRID, IntAct26496610 details
EIF4G1Pabpc1BioGRID, IntAct26496610 details
EIF4G1Rnf183BioGRID31732153 details