Entity Details

Primary name A2M
Entity type gene
Source Source Link

Details

PrimaryID2
RefseqGeneNG_011717
SymbolA2M
Namealpha-2-macroglobulin
Chromosome12
Location12p13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsA2MG_HUMAN

GO terms

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GOName
GO:0001869 negative regulation of complement activation, lectin pathway
GO:0002020 protease binding
GO:0002576 platelet degranulation
GO:0004866 endopeptidase inhibitor activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0019838 growth factor binding
GO:0019899 enzyme binding
GO:0019959 interleukin-8 binding
GO:0019966 interleukin-1 binding
GO:0022617 extracellular matrix disassembly
GO:0031093 platelet alpha granule lumen
GO:0043120 tumor necrosis factor binding
GO:0048306 calcium-dependent protein binding
GO:0048863 stem cell differentiation
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:2000267 negative regulation of blood coagulation, intrinsic pathway

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
A2MPpifIntAct32814053 details
A2MNgfBioGRID7686585 details