Entity Details

Primary name ABCA2
Entity type gene
Source Source Link

Details

PrimaryID20
RefseqGeneNG_011789
SymbolABCA2
NameATP binding cassette subfamily A member 2
Chromosome9
Location9q34.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsABCA2_HUMAN

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0001573 ganglioside metabolic process
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005815 microtubule organizing center
GO:0005886 plasma membrane
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006629 lipid metabolic process
GO:0006684 sphingomyelin metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0006869 lipid transport
GO:0007626 locomotory behavior
GO:0010008 endosome membrane
GO:0010872 regulation of cholesterol esterification
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016887 ATP hydrolysis activity
GO:0031410 cytoplasmic vesicle
GO:0032289 central nervous system myelin formation
GO:0032383 regulation of intracellular cholesterol transport
GO:0032384 negative regulation of intracellular cholesterol transport
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process
GO:0042493 response to drug
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042632 cholesterol homeostasis
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0043231 intracellular membrane-bounded organelle
GO:0046512 sphingosine biosynthetic process
GO:0048545 response to steroid hormone
GO:0055085 transmembrane transport
GO:0060049 regulation of protein glycosylation
GO:0061135 endopeptidase regulator activity
GO:0070723 response to cholesterol
GO:0071072 negative regulation of phospholipid biosynthetic process
GO:0090155 negative regulation of sphingolipid biosynthetic process
GO:0090156 cellular sphingolipid homeostasis
GO:0090370 negative regulation of cholesterol efflux
GO:0099038 ceramide floppase activity
GO:0099040 ceramide translocation
GO:0150104 transport across blood-brain barrier
GO:0150110 negative regulation of cholesterol esterification
GO:1901873 regulation of post-translational protein modification
GO:1902004 positive regulation of amyloid-beta formation
GO:1902993 positive regulation of amyloid precursor protein catabolic process
GO:1904375 regulation of protein localization to cell periphery
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:1905601 negative regulation of receptor-mediated endocytosis involved in cholesterol transport
GO:2000008 regulation of protein localization to cell surface

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ABCA2Myh10BioGRID, IntAct26496610 details
ABCA2Ankfy1BioGRID, IntAct26496610 details