Entity Details

Primary name PDE12
Entity type gene
Source Source Link

Details

PrimaryID201626
RefseqGene
SymbolPDE12
Namephosphodiesterase 12
Chromosome3
Location3p14.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-04-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPDE12_HUMAN

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000958 mitochondrial mRNA catabolic process
GO:0004527 exonuclease activity
GO:0004535 poly(A)-specific ribonuclease activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006397 mRNA processing
GO:0035457 cellular response to interferon-alpha
GO:0044528 regulation of mitochondrial mRNA stability
GO:0045070 positive regulation of viral genome replication
GO:0046872 metal ion binding
GO:0051607 defense response to virus
GO:0060548 negative regulation of cell death
GO:0071346 cellular response to interferon-gamma
GO:0071359 cellular response to dsRNA
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0090324 negative regulation of oxidative phosphorylation
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PDE12RhoaBioGRID, IntAct26496610 details