Entity Details

Primary name EPAS1
Entity type gene
Source Source Link

Details

PrimaryID2034
RefseqGeneNG_016000
SymbolEPAS1
Nameendothelial PAS domain protein 1
Chromosome2
Location2p21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-07
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsEPAS1_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0001892 embryonic placenta development
GO:0001974 blood vessel remodeling
GO:0002027 regulation of heart rate
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007005 mitochondrion organization
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0008134 transcription factor binding
GO:0016567 protein ubiquitination
GO:0016607 nuclear speck
GO:0030218 erythrocyte differentiation
GO:0030324 lung development
GO:0035019 somatic stem cell population maintenance
GO:0035035 histone acetyltransferase binding
GO:0042415 norepinephrine metabolic process
GO:0043129 surfactant homeostasis
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043687 post-translational protein modification
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048469 cell maturation
GO:0048625 myoblast fate commitment
GO:0055072 iron ion homeostasis
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 cellular response to hypoxia
GO:0120162 positive regulation of cold-induced thermogenesis
GO:2000434 regulation of protein neddylation

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
EPAS1Bhlhe41DIP22801492 details
EPAS1Ruvbl1BioGRID18372249 details
EPAS1ArntBioGRID9000051 details