Entity Details

Primary name ERCC2
Entity type gene
Source Source Link

Details

PrimaryID2068
RefseqGeneNG_007067
SymbolERCC2
NameERCC excision repair 2, TFIIH core complex helicase subunit
Chromosome19
Location19q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-01-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsERCC2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000439 transcription factor TFIIH core complex
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0001666 response to hypoxia
GO:0001701 in utero embryonic development
GO:0003678 DNA helicase activity
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005669 transcription factor TFIID complex
GO:0005675 transcription factor TFIIH holo complex
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006362 transcription elongation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0006915 apoptotic process
GO:0006979 response to oxidative stress
GO:0007059 chromosome segregation
GO:0007568 aging
GO:0008022 protein C-terminus binding
GO:0008283 cell population proliferation
GO:0009411 response to UV
GO:0009650 UV protection
GO:0009791 post-embryonic development
GO:0016032 viral process
GO:0021510 spinal cord development
GO:0030198 extracellular matrix organization
GO:0030282 bone mineralization
GO:0030674 protein-macromolecule adaptor activity
GO:0032289 central nervous system myelin formation
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035264 multicellular organism growth
GO:0035315 hair cell differentiation
GO:0040016 embryonic cleavage
GO:0043139 5'-3' DNA helicase activity
GO:0043249 erythrocyte maturation
GO:0043388 positive regulation of DNA binding
GO:0045951 positive regulation of mitotic recombination
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0048568 embryonic organ development
GO:0048820 hair follicle maturation
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0060218 hematopoietic stem cell differentiation
GO:0070516 CAK-ERCC2 complex
GO:0070911 global genome nucleotide-excision repair
GO:0071817 MMXD complex
GO:1901990 regulation of mitotic cell cycle phase transition

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ERCC2Xpo1IntAct26673895 details
ERCC2Prdm16MINT30462309 details
ERCC2MecomMINT30462309 details