Entity Details

Primary name ERCC4
Entity type gene
Source Source Link

Details

PrimaryID2072
RefseqGeneNG_011442
SymbolERCC4
NameERCC excision repair 4, endonuclease catalytic subunit
Chromosome16
Location16p13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsXPF_HUMAN

GO terms

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GOName
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0000109 nucleotide-excision repair complex
GO:0000110 nucleotide-excision repair factor 1 complex
GO:0000712 resolution of meiotic recombination intermediates
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0001094 TFIID-class transcription factor complex binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0004520 endodeoxyribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0008022 protein C-terminus binding
GO:0009411 response to UV
GO:0009650 UV protection
GO:0010506 regulation of autophagy
GO:0032205 negative regulation of telomere maintenance
GO:0033683 nucleotide-excision repair, DNA incision
GO:0034644 cellular response to UV
GO:0036297 interstrand cross-link repair
GO:0042802 identical protein binding
GO:0047485 protein N-terminus binding
GO:0051974 negative regulation of telomerase activity
GO:0061819 telomeric DNA-containing double minutes formation
GO:0070522 ERCC4-ERCC1 complex
GO:0070911 global genome nucleotide-excision repair
GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1905765 negative regulation of protection from non-homologous end joining at telomere
GO:1905768 negative regulation of double-stranded telomeric DNA binding
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ERCC4Slx4BioGRID25722289 details
ERCC4Ddb1BioGRID, IntAct26496610 details
ERCC4Mus81BioGRID, IntAct26496610 details