Entity Details

Primary name F12
Entity type gene
Source Source Link

Details

PrimaryID2161
RefseqGeneNG_007568
SymbolF12
Namecoagulation factor XII
Chromosome5
Location5q35.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-07-29
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFA12_HUMAN

GO terms

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GOName
GO:0002353 plasma kallikrein-kinin cascade
GO:0002542 Factor XII activation
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005791 rough endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0007596 blood coagulation
GO:0007597 blood coagulation, intrinsic pathway
GO:0010756 positive regulation of plasminogen activation
GO:0016485 protein processing
GO:0016540 protein autoprocessing
GO:0030194 positive regulation of blood coagulation
GO:0031638 zymogen activation
GO:0042730 fibrinolysis
GO:0045087 innate immune response
GO:0051787 misfolded protein binding
GO:0051788 response to misfolded protein
GO:0051919 positive regulation of fibrinolysis
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:2000267 negative regulation of blood coagulation, intrinsic pathway

Diseases

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Interactions

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