Entity Details

Primary name FASN
Entity type gene
Source Source Link

Details

PrimaryID2194
RefseqGene
SymbolFASN
Namefatty acid synthase
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-11-03
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFAS_HUMAN

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0002068 glandular epithelial cell development
GO:0003723 RNA binding
GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006084 acetyl-CoA metabolic process
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
GO:0008611 ether lipid biosynthetic process
GO:0008659 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity
GO:0008693 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity
GO:0016020 membrane
GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0019216 regulation of lipid metabolic process
GO:0030223 neutrophil differentiation
GO:0030224 monocyte differentiation
GO:0030522 intracellular receptor signaling pathway
GO:0030879 mammary gland development
GO:0031177 phosphopantetheine binding
GO:0031325 positive regulation of cellular metabolic process
GO:0042470 melanosome
GO:0042587 glycogen granule
GO:0042802 identical protein binding
GO:0045296 cadherin binding
GO:0046949 fatty-acyl-CoA biosynthetic process
GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0070062 extracellular exosome
GO:0071353 cellular response to interleukin-4
GO:0090557 establishment of endothelial intestinal barrier
GO:0102131 3-oxo-glutaryl-[acp] methyl ester reductase activity
GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
FASNYap1BioGRID30865227 details
FASNMapk13BioGRID19135240 details
FASNAI837181BioGRID, IntAct20360068 details
FASNBag2BioGRID, IntAct26496610 details
FASNTubg1BioGRID, IntAct26496610 details
FASNMecomMINT30462309 details
FASNRnf183BioGRID31732153 details