Entity Details

Primary name FEN1
Entity type gene
Source Source Link

Details

PrimaryID2237
RefseqGene
SymbolFEN1
Nameflap structure-specific endonuclease 1
Chromosome11
Location11q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFEN1_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006287 base-excision repair, gap-filling
GO:0006302 double-strand break repair
GO:0007613 memory
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0009650 UV protection
GO:0016020 membrane
GO:0017108 5'-flap endonuclease activity
GO:0030145 manganese ion binding
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032991 protein-containing complex
GO:0043137 DNA replication, removal of RNA primer
GO:0045876 positive regulation of sister chromatid cohesion
GO:0048256 flap endonuclease activity
GO:0090305 nucleic acid phosphodiester bond hydrolysis

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FEN1NelfaBioGRID, IntAct26496610 details
FEN1MecomMINT30462309 details
FEN1Ksr1BioGRID26549023 details