Entity Details

Primary name FGFR1
Entity type gene
Source Source Link

Details

PrimaryID2260
RefseqGeneNG_007729
SymbolFGFR1
Namefibroblast growth factor receptor 1
Chromosome8
Location8p11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsFGFR1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001501 skeletal system development
GO:0001764 neuron migration
GO:0001837 epithelial to mesenchymal transition
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010518 positive regulation of phospholipase activity
GO:0010863 positive regulation of phospholipase C activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0017134 fibroblast growth factor binding
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0031410 cytoplasmic vesicle
GO:0033674 positive regulation of kinase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043009 chordate embryonic development
GO:0043235 receptor complex
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045595 regulation of cell differentiation
GO:0045597 positive regulation of cell differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0046777 protein autophosphorylation
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048705 skeletal system morphogenesis
GO:0051897 positive regulation of protein kinase B signaling
GO:0090722 receptor-receptor interaction
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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Interactions

5 interactions