Entity Details

Primary name FGFR3
Entity type gene
Source Source Link

Details

PrimaryID2261
RefseqGeneNG_012632
SymbolFGFR3
Namefibroblast growth factor receptor 3
Chromosome4
Location4p16.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFGFR3_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001501 skeletal system development
GO:0001958 endochondral ossification
GO:0002062 chondrocyte differentiation
GO:0003416 endochondral bone growth
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009986 cell surface
GO:0010518 positive regulation of phospholipase activity
GO:0017134 fibroblast growth factor binding
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030133 transport vesicle
GO:0030282 bone mineralization
GO:0033674 positive regulation of kinase activity
GO:0035988 chondrocyte proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0046777 protein autophosphorylation
GO:0048640 negative regulation of developmental growth
GO:0051897 positive regulation of protein kinase B signaling
GO:0060349 bone morphogenesis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070977 bone maturation
GO:1902178 fibroblast growth factor receptor apoptotic signaling pathway

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
FGFR3Sh2b1BioGRID11827956 details