Entity Details

Primary name XRN2
Entity type gene
Source Source Link

Details

PrimaryID22803
RefseqGene
SymbolXRN2
Name5'-3' exoribonuclease 2
Chromosome20
Location20p11.22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsXRN2_HUMAN

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000738 DNA catabolic process, exonucleolytic
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0001147 transcription termination site sequence-specific DNA binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0004534 5'-3' exoribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0006401 RNA catabolic process
GO:0007283 spermatogenesis
GO:0008409 5'-3' exonuclease activity
GO:0016020 membrane
GO:0016070 RNA metabolic process
GO:0016235 aggresome
GO:0021766 hippocampus development
GO:0030182 neuron differentiation
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0060041 retina development in camera-type eye

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
XRN2TipinBioGRID, IntAct26496610 details
XRN2Cdkn2aipBioGRID, IntAct26496610 details
XRN2MecomMINT30462309 details
XRN2Arhgap8BioGRID, IntAct32203420 details