Entity Details

Primary name AAK1
Entity type gene
Source Source Link

Details

PrimaryID22848
RefseqGene
SymbolAAK1
NameAP2 associated kinase 1
Chromosome2
Location2p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAAK1_HUMAN

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005112 Notch binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005905 clathrin-coated pit
GO:0006468 protein phosphorylation
GO:0006897 endocytosis
GO:0019897 extrinsic component of plasma membrane
GO:0030136 clathrin-coated vesicle
GO:0031252 cell leading edge
GO:0032880 regulation of protein localization
GO:0035612 AP-2 adaptor complex binding
GO:0043195 terminal bouton
GO:0045747 positive regulation of Notch signaling pathway
GO:0046777 protein autophosphorylation
GO:0050821 protein stabilization
GO:0061024 membrane organization
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000369 regulation of clathrin-dependent endocytosis

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
AAK1Ppp1cbBioGRID, IntAct26496610 details
AAK1ActbBioGRID, IntAct26496610 details
AAK1Lima1BioGRID, IntAct26496610 details
AAK1Myh9BioGRID, IntAct26496610 details
AAK1Myo1cBioGRID, IntAct26496610 details
AAK1Xpo1IntAct26673895 details