Entity Details

Primary name FLNA
Entity type gene
Source Source Link

Details

PrimaryID2316
RefseqGeneNG_011506
SymbolFLNA
Namefilamin A
ChromosomeX
LocationXq28
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-02
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsFLNA_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001664 G protein-coupled receptor binding
GO:0001837 epithelial to mesenchymal transition
GO:0001974 blood vessel remodeling
GO:0002576 platelet degranulation
GO:0003007 heart morphogenesis
GO:0003723 RNA binding
GO:0005080 protein kinase C binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0008134 transcription factor binding
GO:0010977 negative regulation of neuron projection development
GO:0015459 potassium channel regulator activity
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016479 negative regulation of transcription by RNA polymerase I
GO:0019900 kinase binding
GO:0021943 formation of radial glial scaffolds
GO:0021987 cerebral cortex development
GO:0030018 Z disc
GO:0030168 platelet activation
GO:0030334 regulation of cell migration
GO:0030863 cortical cytoskeleton
GO:0031267 small GTPase binding
GO:0031523 Myb complex
GO:0031532 actin cytoskeleton reorganization
GO:0031852 mu-type opioid receptor binding
GO:0032233 positive regulation of actin filament bundle assembly
GO:0032432 actin filament bundle
GO:0034329 cell junction assembly
GO:0034394 protein localization to cell surface
GO:0034988 Fc-gamma receptor I complex binding
GO:0042177 negative regulation of protein catabolic process
GO:0042307 positive regulation of protein import into nucleus
GO:0042789 mRNA transcription by RNA polymerase II
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043113 receptor clustering
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043198 dendritic shaft
GO:0043204 perikaryon
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0044295 axonal growth cone
GO:0044319 wound healing, spreading of cells
GO:0044325 transmembrane transporter binding
GO:0045022 early endosome to late endosome transport
GO:0045184 establishment of protein localization
GO:0045216 cell-cell junction organization
GO:0045296 cadherin binding
GO:0046332 SMAD binding
GO:0048471 perinuclear region of cytoplasm
GO:0048680 positive regulation of axon regeneration
GO:0050808 synapse organization
GO:0050821 protein stabilization
GO:0051015 actin filament binding
GO:0051020 GTPase binding
GO:0051220 cytoplasmic sequestering of protein
GO:0051607 defense response to virus
GO:0051764 actin crosslink formation
GO:0060271 cilium assembly
GO:0070062 extracellular exosome
GO:0070527 platelet aggregation
GO:0071526 semaphorin-plexin signaling pathway
GO:0072659 protein localization to plasma membrane
GO:0090042 tubulin deacetylation
GO:0090307 mitotic spindle assembly
GO:0097368 establishment of Sertoli cell barrier
GO:0097440 apical dendrite
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901381 positive regulation of potassium ion transmembrane transport
GO:1902396 protein localization to bicellular tight junction
GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential
GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2001046 positive regulation of integrin-mediated signaling pathway
GO:2001224 positive regulation of neuron migration

Diseases

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Interactions

21 interactions

InteractorPartnerSourcesPublicationsLink
FLNARacgap1BioGRID, IntAct26496610 details
FLNANek2BioGRID, IntAct26496610 details
FLNAFlot1BioGRID, IntAct26496610 details
FLNAFlot2BioGRID, IntAct26496610 details
FLNAMyh10BioGRID, IntAct26496610 details
FLNAActbBioGRID, IntAct26496610 details
FLNAFlnbBioGRID, IntAct26496610 details
FLNALima1BioGRID, IntAct26496610 details
FLNACalml3BioGRID, IntAct26496610 details
FLNATmod3BioGRID, IntAct26496610 details
FLNATpm1BioGRID, IntAct26496610 details
FLNACoro1cBioGRID, IntAct26496610 details
FLNAMyh9BioGRID, IntAct26496610 details
FLNAMyo1cBioGRID, IntAct26496610 details
FLNAArrb2BioGRID, IntAct26496610 details
FLNAItga5BioGRID, IntAct26496610 details
FLNAPrkaa1BioGRID, IntAct26496610 details
FLNASeptin9BioGRID, IntAct26496610 details
FLNAPrdm16MINT30462309 details
FLNAMecomMINT30462309 details
FLNARnf183BioGRID31732153 details