Entity Details

Primary name NEDD4L
Entity type gene
Source Source Link

Details

PrimaryID23327
RefseqGeneNG_029954
SymbolNEDD4L
NameNEDD4 like E3 ubiquitin protein ligase
Chromosome18
Location18q21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-19
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsNED4L_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000209 protein polyubiquitination
GO:0003254 regulation of membrane depolarization
GO:0004842 ubiquitin-protein transferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005771 multivesicular body
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006814 sodium ion transport
GO:0006883 cellular sodium ion homeostasis
GO:0007588 excretion
GO:0010038 response to metal ion
GO:0015459 potassium channel regulator activity
GO:0016567 protein ubiquitination
GO:0017080 sodium channel regulator activity
GO:0019058 viral life cycle
GO:0019870 potassium channel inhibitor activity
GO:0019871 sodium channel inhibitor activity
GO:0030104 water homeostasis
GO:0030154 cell differentiation
GO:0031647 regulation of protein stability
GO:0034220 ion transmembrane transport
GO:0034765 regulation of ion transmembrane transport
GO:0042176 regulation of protein catabolic process
GO:0042391 regulation of membrane potential
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044325 transmembrane transporter binding
GO:0045732 positive regulation of protein catabolic process
GO:0045807 positive regulation of endocytosis
GO:0048814 regulation of dendrite morphogenesis
GO:0060306 regulation of membrane repolarization
GO:0061630 ubiquitin protein ligase activity
GO:0070062 extracellular exosome
GO:0070936 protein K48-linked ubiquitination
GO:0086005 ventricular cardiac muscle cell action potential
GO:1901016 regulation of potassium ion transmembrane transporter activity
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1902306 negative regulation of sodium ion transmembrane transport
GO:1903861 positive regulation of dendrite extension
GO:2000009 negative regulation of protein localization to cell surface
GO:2000650 negative regulation of sodium ion transmembrane transporter activity
GO:2001288 positive regulation of caveolin-mediated endocytosis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
NEDD4LPi4k2aBioGRID23146885 details
NEDD4LNdfip1BioGRID11748237 details
NEDD4LLpar1BioGRID27448760 details
NEDD4LXpo1IntAct26673895 details