Entity Details

Primary name SRGAP2
Entity type gene
Source Source Link

Details

PrimaryID23380
RefseqGeneNG_033804
SymbolSRGAP2
NameSLIT-ROBO Rho GTPase activating protein 2
Chromosome1
Location1q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSRGP2_HUMAN

GO terms

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GOName
GO:0003363 lamellipodium assembly involved in ameboidal cell migration
GO:0005096 GTPase activator activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0014069 postsynaptic density
GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
GO:0030027 lamellipodium
GO:0030336 negative regulation of cell migration
GO:0031267 small GTPase binding
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043547 positive regulation of GTPase activity
GO:0044327 dendritic spine head
GO:0045211 postsynaptic membrane
GO:0045335 phagocytic vesicle
GO:0046847 filopodium assembly
GO:0048812 neuron projection morphogenesis
GO:0051014 actin filament severing
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0060996 dendritic spine development
GO:2001223 negative regulation of neuron migration

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SRGAP2Fmnl3UniProt21148482 details
SRGAP2Fmnl1UniProt21148482 details
SRGAP2ActbBioGRID, IntAct26496610 details