Entity Details

Primary name NNT
Entity type gene
Source Source Link

Details

PrimaryID23530
RefseqGeneNG_032869
SymbolNNT
Namenicotinamide nucleotide transhydrogenase
Chromosome5
Location5p12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNNTM_HUMAN

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005746 mitochondrial respirasome
GO:0006099 tricarboxylic acid cycle
GO:0006740 NADPH regeneration
GO:0008746 NAD(P)+ transhydrogenase activity
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032364 oxygen homeostasis
GO:0033273 response to vitamin
GO:0043066 negative regulation of apoptotic process
GO:0045454 cell redox homeostasis
GO:0050661 NADP binding
GO:0051287 NAD binding
GO:0072593 reactive oxygen species metabolic process
GO:0098869 cellular oxidant detoxification
GO:1902600 proton transmembrane transport
GO:1903285 positive regulation of hydrogen peroxide catabolic process

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
NNTPapss1BioGRID, IntAct26496610 details
NNTCdc26BioGRID, IntAct26496610 details
NNTMkln1BioGRID, IntAct26496610 details
NNTWizBioGRID, IntAct26496610 details
NNTMis12BioGRID, IntAct26496610 details
NNTJunbBioGRID, IntAct26496610 details
NNTPrdm16MINT30462309 details
NNTMecomMINT30462309 details