Entity Details

Primary name DDX58
Entity type gene
Source Source Link

Details

PrimaryID23586
RefseqGeneNG_046918
SymbolDDX58
NameDExD/H-box helicase 58
Chromosome9
Location9p21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-10-25
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsDDX58_HUMAN

GO terms

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GOName
GO:0002230 positive regulation of defense response to virus by host
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0008270 zinc ion binding
GO:0009597 detection of virus
GO:0009615 response to virus
GO:0010628 positive regulation of gene expression
GO:0015629 actin cytoskeleton
GO:0016032 viral process
GO:0016579 protein deubiquitination
GO:0016787 hydrolase activity
GO:0030334 regulation of cell migration
GO:0031625 ubiquitin protein ligase binding
GO:0032480 negative regulation of type I interferon production
GO:0032587 ruffle membrane
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034344 regulation of type III interferon production
GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus
GO:0039529 RIG-I signaling pathway
GO:0042802 identical protein binding
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051607 defense response to virus
GO:0060760 positive regulation of response to cytokine stimulus
GO:0071360 cellular response to exogenous dsRNA
GO:0140374 antiviral innate immune response
GO:1990904 ribonucleoprotein complex

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DDX58Casp12BioGRID20818395 details
DDX58Trim25BioGRID20818395 details