Entity Details

Primary name BACE2
Entity type gene
Source Source Link

Details

PrimaryID25825
RefseqGene
SymbolBACE2
Namebeta-secretase 2
Chromosome21
Location21q22.2-q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBACE2_HUMAN

GO terms

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GOName
GO:0004190 aspartic-type endopeptidase activity
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016486 peptide hormone processing
GO:0031045 dense core granule
GO:0042593 glucose homeostasis
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process
GO:0048143 astrocyte activation
GO:0050435 amyloid-beta metabolic process

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
BACE2IappUniProt26840340 details