Entity Details

Primary name POT1
Entity type gene
Source Source Link

Details

PrimaryID25913
RefseqGeneNG_029232
SymbolPOT1
Nameprotection of telomeres 1
Chromosome7
Location7q31.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-21
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsPOTE1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000783 nuclear telomere cap complex
GO:0005654 nucleoplasm
GO:0007004 telomere maintenance via telomerase
GO:0010521 telomerase inhibitor activity
GO:0016233 telomere capping
GO:0017151 DEAD/H-box RNA helicase binding
GO:0032201 telomere maintenance via semi-conservative replication
GO:0032202 telomere assembly
GO:0032210 regulation of telomere maintenance via telomerase
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032508 DNA duplex unwinding
GO:0042162 telomeric DNA binding
GO:0043047 single-stranded telomeric DNA binding
GO:0045007 depurination
GO:0048239 negative regulation of DNA recombination at telomere
GO:0051096 positive regulation of helicase activity
GO:0051973 positive regulation of telomerase activity
GO:0051974 negative regulation of telomerase activity
GO:0060383 positive regulation of DNA strand elongation
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding
GO:0070187 shelterin complex
GO:0070200 establishment of protein localization to telomere
GO:0098505 G-rich strand telomeric DNA binding
GO:1900051 positive regulation of histone exchange
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding
GO:1905774 regulation of DNA helicase activity
GO:1905776 positive regulation of DNA helicase activity
GO:1990955 G-rich single-stranded DNA binding
GO:2001032 regulation of double-strand break repair via nonhomologous end joining

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
POT1AcdDIP17632522 details
POT1Terf1BioGRID, IntAct26496610 details
POT1Dclre1bBioGRID, IntAct26496610 details