Entity Details

Primary name GART
Entity type gene
Source Source Link

Details

PrimaryID2618
RefseqGeneNG_029160
SymbolGART
Namephosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Chromosome21
Location21q22.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-11-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPUR2_HUMAN

GO terms

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GOName
GO:0003360 brainstem development
GO:0004637 phosphoribosylamine-glycine ligase activity
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004644 phosphoribosylglycinamide formyltransferase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0006544 glycine metabolic process
GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0010033 response to organic substance
GO:0010035 response to inorganic substance
GO:0021549 cerebellum development
GO:0021987 cerebral cortex development
GO:0046084 adenine biosynthetic process
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046872 metal ion binding
GO:0070062 extracellular exosome

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
GARTBmpr1aBioGRID, IntAct26496610 details
GARTBag2BioGRID, IntAct26496610 details
GARTCalml3BioGRID, IntAct26496610 details
GARTMyh9BioGRID, IntAct26496610 details
GARTArhgap30BioGRID, IntAct32203420 details
GARTRnf183BioGRID31732153 details