Entity Details

Primary name AGO1
Entity type gene
Source Source Link

Details

PrimaryID26523
RefseqGene
SymbolAGO1
Nameargonaute RISC component 1
Chromosome1
Location1p34.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsAGO1_HUMAN

GO terms

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GOName
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0000993 RNA polymerase II complex binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005844 polysome
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0010501 RNA secondary structure unwinding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016442 RISC complex
GO:0016525 negative regulation of angiogenesis
GO:0030522 intracellular receptor signaling pathway
GO:0031054 pre-miRNA processing
GO:0035194 post-transcriptional gene silencing by RNA
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035198 miRNA binding
GO:0035278 miRNA mediated inhibition of translation
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0045652 regulation of megakaryocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0060964 regulation of gene silencing by miRNA
GO:0070578 RISC-loading complex
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
GO:1990904 ribonucleoprotein complex

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AGO1Trim32IntAct19269368 details
AGO1Smad6MINT23455153 details