Entity Details

Primary name 1433S_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70456
EntryName1433S_MOUSE
FullName14-3-3 protein sigma
TaxID10090
Evidenceevidence at protein level
Length248
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesSfn

GO terms

Show/Hide Table
GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001836 release of cytochrome c from mitochondria
GO:0003334 keratinocyte development
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010482 regulation of epidermal cell division
GO:0010839 negative regulation of keratinocyte proliferation
GO:0019901 protein kinase binding
GO:0030216 keratinocyte differentiation
GO:0030307 positive regulation of cell growth
GO:0031424 keratinization
GO:0042802 identical protein binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 skin development
GO:0045606 positive regulation of epidermal cell differentiation
GO:0046827 positive regulation of protein export from nucleus
GO:0051219 phosphoprotein binding
GO:0051726 regulation of cell cycle
GO:0061436 establishment of skin barrier

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000308 14-3-3 proteinFamilyFamily
IPR023409 14-3-3 protein, conserved siteSiteConserved site
IPR023410 14-3-3 domainDomainDomain
IPR036815 14-3-3 domain superfamilyFamilyHomologous superfamily
IPR037435 14-3-3 protein sigmaFamilyFamily

Diseases

Show/Hide Table