Entity Details

Primary name EXOS8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D753
EntryNameEXOS8_MOUSE
FullNameExosome complex component RRP43
TaxID10090
Evidenceevidence at protein level
Length276
SequenceStatuscomplete
DateCreated2002-07-11
DateModified2021-06-02

Ontological Relatives

GenesExosc8

GO terms

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GOName
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016075 rRNA catabolic process
GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0034473 U1 snRNA 3'-end processing
GO:0034475 U4 snRNA 3'-end processing
GO:0034476 U5 snRNA 3'-end processing
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0071028 nuclear mRNA surveillance
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001247 Exoribonuclease, phosphorolytic domain 1DomainDomain
IPR015847 Exoribonuclease, phosphorolytic domain 2DomainDomain
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027408 PNPase/RNase PH domain superfamilyFamilyHomologous superfamily
IPR033196 Exosome complex component Rrp43FamilyFamily
IPR036345 Exoribonuclease, PH domain 2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
EXOS8_MOUSEOTUD4_HUMANBioGRID31138677 details