Entity Details

Primary name GNAS
Entity type gene
Source Source Link

Details

PrimaryID2778
RefseqGeneNG_016194
SymbolGNAS
NameGNAS complex locus
Chromosome20
Location20q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-04-06
ModificationDate2021-06-20

Ontological Relatives

GO terms

Show/Hide Table
GOName
GO:0001664 G protein-coupled receptor binding
GO:0001726 ruffle
GO:0001894 tissue homeostasis
GO:0001958 endochondral ossification
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0003924 GTPase activity
GO:0005159 insulin-like growth factor receptor binding
GO:0005525 GTP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0006112 energy reserve metabolic process
GO:0006306 DNA methylation
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007565 female pregnancy
GO:0007606 sensory perception of chemical stimulus
GO:0007608 sensory perception of smell
GO:0009306 protein secretion
GO:0009966 regulation of signal transduction
GO:0010856 adenylate cyclase activator activity
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0030133 transport vesicle
GO:0030425 dendrite
GO:0031224 intrinsic component of membrane
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031698 beta-2 adrenergic receptor binding
GO:0031748 D1 dopamine receptor binding
GO:0031852 mu-type opioid receptor binding
GO:0032588 trans-Golgi network membrane
GO:0035116 embryonic hindlimb morphogenesis
GO:0035255 ionotropic glutamate receptor binding
GO:0035264 multicellular organism growth
GO:0040015 negative regulation of multicellular organism growth
GO:0040032 post-embryonic body morphogenesis
GO:0042493 response to drug
GO:0043547 positive regulation of GTPase activity
GO:0043588 skin development
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0045669 positive regulation of osteoblast differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0046872 metal ion binding
GO:0046907 intracellular transport
GO:0048471 perinuclear region of cytoplasm
GO:0048589 developmental growth
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0050796 regulation of insulin secretion
GO:0050890 cognition
GO:0051216 cartilage development
GO:0051430 corticotropin-releasing hormone receptor 1 binding
GO:0060348 bone development
GO:0060789 hair follicle placode formation
GO:0070062 extracellular exosome
GO:0070527 platelet aggregation
GO:0071107 response to parathyroid hormone
GO:0071377 cellular response to glucagon stimulus
GO:0071380 cellular response to prostaglandin E stimulus
GO:0071514 genetic imprinting
GO:0071870 cellular response to catecholamine stimulus
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0120162 positive regulation of cold-induced thermogenesis
GO:2000828 regulation of parathyroid hormone secretion

Diseases

Show/Hide Table

Interactions

15 interactions

InteractorPartnerSourcesPublicationsLink
GNASRic8bBioGRID20133939 details
GNASOprm1MINT22177524 details
GNASCoro1aMINT26823173 details
GNASCbx1BioGRID, IntAct20360068 details
GNASTrim69BioGRID, IntAct20360068 details
GNASHaus1BioGRID, IntAct20360068 details
GNASRmdn3BioGRID, IntAct26496610 details
GNASFlot2BioGRID, IntAct26496610 details
GNASActbBioGRID, IntAct26496610 details
GNASLima1BioGRID, IntAct26496610 details
GNASCalml3BioGRID, IntAct26496610 details
GNASCoro1cBioGRID, IntAct26496610 details
GNASMaxBioGRID, IntAct26496610 details
GNASSmc1aBioGRID, IntAct26496610 details
GNASXpo1IntAct26673895 details