Entity Details

Primary name SFN
Entity type gene
Source Source Link

Details

PrimaryID2810
RefseqGene
SymbolSFN
Namestratifin
Chromosome1
Location1p36.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDs1433S_HUMAN

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0001836 release of cytochrome c from mitochondria
GO:0003334 keratinocyte development
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006469 negative regulation of protein kinase activity
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 signal transduction
GO:0008426 protein kinase C inhibitor activity
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010482 regulation of epidermal cell division
GO:0010839 negative regulation of keratinocyte proliferation
GO:0019901 protein kinase binding
GO:0030307 positive regulation of cell growth
GO:0031424 keratinization
GO:0042802 identical protein binding
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045296 cadherin binding
GO:0045606 positive regulation of epidermal cell differentiation
GO:0046827 positive regulation of protein export from nucleus
GO:0051219 phosphoprotein binding
GO:0061436 establishment of skin barrier
GO:0070062 extracellular exosome
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SFNBadMINT11697890 details
SFNRnd3IntAct23622247 details
SFNHerc2BioGRID, IntAct26496610 details
SFNXpo7IntAct29748336 unassigned1673 details