Entity Details

Primary name PRPS1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D7G0
EntryNamePRPS1_MOUSE
FullNameRibose-phosphate pyrophosphokinase 1
TaxID10090
Evidenceevidence at protein level
Length318
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesPrps1

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002189 ribose phosphate diphosphokinase complex
GO:0004749 ribose phosphate diphosphokinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006144 purine nucleobase metabolic process
GO:0006164 purine nucleotide biosynthetic process
GO:0006167 AMP biosynthetic process
GO:0007399 nervous system development
GO:0009116 nucleoside metabolic process
GO:0009165 nucleotide biosynthetic process
GO:0016208 AMP binding
GO:0016301 kinase activity
GO:0019003 GDP binding
GO:0019693 ribose phosphate metabolic process
GO:0030246 carbohydrate binding
GO:0032991 protein-containing complex
GO:0034418 urate biosynthetic process
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043531 ADP binding
GO:0046101 hypoxanthine biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000836 Phosphoribosyltransferase domainDomainDomain
IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved siteSiteConserved site
IPR005946 Ribose-phosphate pyrophosphokinaseFamilyFamily
IPR029057 Phosphoribosyltransferase-likeFamilyHomologous superfamily
IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domainDomainDomain
IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-typeFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PRPS1_MOUSEPRKN_MOUSEBioGRID22792159 details