Entity Details

Primary name NSMCE2
Entity type gene
Source Source Link

Details

PrimaryID286053
RefseqGeneNG_053069
SymbolNSMCE2
NameNSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
Chromosome8
Location8q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-12-14
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNSE2_HUMAN

GO terms

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GOName
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0016604 nuclear body
GO:0016605 PML body
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0030915 Smc5-Smc6 complex
GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0051301 cell division
GO:0061665 SUMO ligase activity
GO:0090398 cellular senescence

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
NSMCE2Smc6BioGRID, IntAct20360068 details
NSMCE2LckBioGRID, IntAct26496610 details
NSMCE2Rbm8aBioGRID, IntAct26496610 details
NSMCE2Tgfbr1BioGRID, IntAct26496610 details