Entity Details

Primary name GRIN1
Entity type gene
Source Source Link

Details

PrimaryID2902
RefseqGeneNG_011507
SymbolGRIN1
Nameglutamate ionotropic receptor NMDA type subunit 1
Chromosome9
Location9q34.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-01-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNMDZ1_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001540 amyloid-beta binding
GO:0004972 NMDA glutamate receptor activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006812 cation transport
GO:0007268 chemical synaptic transmission
GO:0007420 brain development
GO:0008021 synaptic vesicle
GO:0008542 visual learning
GO:0009986 cell surface
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0014069 postsynaptic density
GO:0015276 ligand-gated ion channel activity
GO:0016594 glycine binding
GO:0016595 glutamate binding
GO:0017146 NMDA selective glutamate receptor complex
GO:0018964 propylene metabolic process
GO:0022849 glutamate-gated calcium ion channel activity
GO:0030425 dendrite
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0038023 signaling receptor activity
GO:0042165 neurotransmitter binding
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0043083 synaptic cleft
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045471 response to ethanol
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048013 ephrin receptor signaling pathway
GO:0048167 regulation of synaptic plasticity
GO:0051290 protein heterotetramerization
GO:0055074 calcium ion homeostasis
GO:0060076 excitatory synapse
GO:0060079 excitatory postsynaptic potential
GO:0097060 synaptic membrane
GO:0097553 calcium ion transmembrane import into cytosol
GO:0098976 excitatory chemical synaptic transmission
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1905429 response to glycine
GO:2000310 regulation of NMDA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
GRIN1Tiam2MINT19893486 details
GRIN1Dlg4BioGRID15255944 details
GRIN1Grin2aBioGRID11897110 details