Entity Details

Primary name SETD2
Entity type gene
Source Source Link

Details

PrimaryID29072
RefseqGeneNG_032091
SymbolSETD2
NameSET domain containing 2, histone lysine methyltransferase
Chromosome3
Location3p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-08
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSETD2_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001763 morphogenesis of a branching structure
GO:0001843 neural tube closure
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0006298 mismatch repair
GO:0006355 regulation of transcription, DNA-templated
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0010793 regulation of mRNA export from nucleus
GO:0016032 viral process
GO:0016279 protein-lysine N-methyltransferase activity
GO:0018023 peptidyl-lysine trimethylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0018026 peptidyl-lysine monomethylation
GO:0030900 forebrain development
GO:0032465 regulation of cytokinesis
GO:0032727 positive regulation of interferon-alpha production
GO:0034340 response to type I interferon
GO:0034728 nucleosome organization
GO:0035441 cell migration involved in vasculogenesis
GO:0035987 endodermal cell differentiation
GO:0043014 alpha-tubulin binding
GO:0046872 metal ion binding
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0048332 mesoderm morphogenesis
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048863 stem cell differentiation
GO:0048864 stem cell development
GO:0051607 defense response to virus
GO:0060039 pericardium development
GO:0060669 embryonic placenta morphogenesis
GO:0060977 coronary vasculature morphogenesis
GO:0097198 histone H3-K36 trimethylation
GO:0097676 histone H3-K36 dimethylation
GO:1902850 microtubule cytoskeleton organization involved in mitosis
GO:1905634 regulation of protein localization to chromatin

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SETD2Ttll7BioGRID, IntAct26496610 details
SETD2Xpo1IntAct26673895 details