Entity Details

Primary name NR3C1
Entity type gene
Source Source Link

Details

PrimaryID2908
RefseqGeneNG_009062
SymbolNR3C1
Namenuclear receptor subfamily 3 group C member 1
Chromosome5
Location5q31.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsGCR_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001046 core promoter sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0003723 RNA binding
GO:0004879 nuclear receptor activity
GO:0004883 glucocorticoid receptor activity
GO:0005496 steroid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0007165 signal transduction
GO:0008270 zinc ion binding
GO:0016607 nuclear speck
GO:0019901 protein kinase binding
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0032991 protein-containing complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051301 cell division
GO:0051879 Hsp90 protein binding
GO:0071383 cellular response to steroid hormone stimulus
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071549 cellular response to dexamethasone stimulus
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1990239 steroid hormone binding
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
NR3C1Asxl1UniProt16606617 details
NR3C1Pou3f3BioGRID11997177 details
NR3C1Cry1DIP22170608 details
NR3C1Ncoa2IntAct26031419 details
NR3C1Tube1BioGRID, IntAct26496610 details