Entity Details

Primary name DROSHA
Entity type gene
Source Source Link

Details

PrimaryID29102
RefseqGeneNG_051574
SymbolDROSHA
Namedrosha ribonuclease III
Chromosome5
Location5p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-03-05
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsRNC_HUMAN

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006396 RNA processing
GO:0010586 miRNA metabolic process
GO:0010628 positive regulation of gene expression
GO:0014069 postsynaptic density
GO:0016075 rRNA catabolic process
GO:0017151 DEAD/H-box RNA helicase binding
GO:0030422 production of siRNA involved in RNA interference
GO:0031053 primary miRNA processing
GO:0031054 pre-miRNA processing
GO:0042254 ribosome biogenesis
GO:0042803 protein homodimerization activity
GO:0045589 regulation of regulatory T cell differentiation
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0050727 regulation of inflammatory response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0070412 R-SMAD binding
GO:0070877 microprocessor complex
GO:0070878 primary miRNA binding
GO:2000628 regulation of miRNA metabolic process

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
DROSHADync1li1BioGRID, IntAct26496610 details
DROSHAPsmb4BioGRID, IntAct26496610 details
DROSHAXpo1IntAct26673895 details