Entity Details

Primary name TBK1
Entity type gene
Source Source Link

Details

PrimaryID29110
RefseqGeneNG_046906
SymbolTBK1
NameTANK binding kinase 1
Chromosome12
Location12q14.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-03-05
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsTBK1_HUMAN

GO terms

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GOName
GO:0002218 activation of innate immune response
GO:0003676 nucleic acid binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006954 inflammatory response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0009615 response to virus
GO:0016032 viral process
GO:0016239 positive regulation of macroautophagy
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019903 protein phosphatase binding
GO:0032479 regulation of type I interferon production
GO:0032480 negative regulation of type I interferon production
GO:0032481 positive regulation of type I interferon production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 intracellular membrane-bounded organelle
GO:0044565 dendritic cell proliferation
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050830 defense response to Gram-positive bacterium
GO:0051219 phosphoprotein binding
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0071345 cellular response to cytokine stimulus
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901214 regulation of neuron death
GO:1904417 positive regulation of xenophagy

Diseases

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