Entity Details

Primary name GSK3A
Entity type gene
Source Source Link

Details

PrimaryID2931
RefseqGene
SymbolGSK3A
Nameglycogen synthase kinase 3 alpha
Chromosome19
Location19q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGSK3A_HUMAN

GO terms

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GOName
GO:0003073 regulation of systemic arterial blood pressure
GO:0003214 cardiac left ventricle morphogenesis
GO:0004674 protein serine/threonine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005977 glycogen metabolic process
GO:0006349 regulation of gene expression by genetic imprinting
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007212 dopamine receptor signaling pathway
GO:0007399 nervous system development
GO:0007568 aging
GO:0008286 insulin receptor signaling pathway
GO:0010508 positive regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0010905 negative regulation of UDP-glucose catabolic process
GO:0010975 regulation of neuron projection development
GO:0016055 Wnt signaling pathway
GO:0016477 cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030424 axon
GO:0030877 beta-catenin destruction complex
GO:0031398 positive regulation of protein ubiquitination
GO:0032007 negative regulation of TOR signaling
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032869 cellular response to insulin stimulus
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034236 protein kinase A catalytic subunit binding
GO:0036016 cellular response to interleukin-3
GO:0036498 IRE1-mediated unfolded protein response
GO:0043025 neuronal cell body
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0044027 hypermethylation of CpG island
GO:0045719 negative regulation of glycogen biosynthetic process
GO:0045732 positive regulation of protein catabolic process
GO:0045823 positive regulation of heart contraction
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0048156 tau protein binding
GO:0050321 tau-protein kinase activity
GO:0060079 excitatory postsynaptic potential
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development
GO:0071285 cellular response to lithium ion
GO:0071879 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097440 apical dendrite
GO:0098794 postsynapse
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902004 positive regulation of amyloid-beta formation
GO:1903146 regulation of autophagy of mitochondrion
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:1904227 negative regulation of glycogen synthase activity, transferring glucose-1-phosphate
GO:1990635 proximal dendrite
GO:2000077 negative regulation of type B pancreatic cell development
GO:2000171 negative regulation of dendrite development
GO:2000466 negative regulation of glycogen (starch) synthase activity
GO:2000467 positive regulation of glycogen (starch) synthase activity

Diseases

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Interactions

14 interactions

InteractorPartnerSourcesPublicationsLink
GSK3AAxin1BioGRID, IntAct20368287 details
GSK3ASpice1BioGRID, IntAct20368287 details
GSK3ADeaf1BioGRID, IntAct20368287 details
GSK3ALzts2BioGRID, IntAct20368287 details
GSK3AMap3k11BioGRID, IntAct20368287 details
GSK3ANbr1BioGRID, IntAct20368287 details
GSK3ANonoBioGRID, IntAct20368287 details
GSK3APrune1BioGRID, IntAct20368287 details
GSK3AVta1BioGRID, IntAct20368287 details
GSK3AProx2BioGRID, IntAct20368287 details
GSK3AKrba1BioGRID, IntAct20368287 details
GSK3AZbed3BioGRID, IntAct20368287 details
GSK3ADact1UniProt21718540 details
GSK3ADact2UniProt21718540 details