Entity Details

Primary name MSH6
Entity type gene
Source Source Link

Details

PrimaryID2956
RefseqGeneNG_007111
SymbolMSH6
NamemutS homolog 6
Chromosome2
Location2p16.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-16
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMSH6_HUMAN

GO terms

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GOName
GO:0000710 meiotic mismatch repair
GO:0000785 chromatin
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006290 pyrimidine dimer repair
GO:0006298 mismatch repair
GO:0008094 ATPase, acting on DNA
GO:0008340 determination of adult lifespan
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 response to UV
GO:0016032 viral process
GO:0016446 somatic hypermutation of immunoglobulin genes
GO:0016447 somatic recombination of immunoglobulin gene segments
GO:0019899 enzyme binding
GO:0030983 mismatched DNA binding
GO:0032137 guanine/thymine mispair binding
GO:0032300 mismatch repair complex
GO:0032301 MutSalpha complex
GO:0035064 methylated histone binding
GO:0036297 interstrand cross-link repair
GO:0043231 intracellular membrane-bounded organelle
GO:0045190 isotype switching
GO:0045910 negative regulation of DNA recombination
GO:0051096 positive regulation of helicase activity
GO:0097193 intrinsic apoptotic signaling pathway

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
MSH6AireIntAct20085707 details
MSH6Eif3iBioGRID, IntAct26496610 details
MSH6Prdm16MINT30462309 details
MSH6MecomMINT30462309 details
MSH6Ksr1BioGRID26549023 details