Entity Details

Primary name HCK
Entity type gene
Source Source Link

Details

PrimaryID3055
RefseqGeneNG_029471
SymbolHCK
NameHCK proto-oncogene, Src family tyrosine kinase
Chromosome20
Location20q11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHCK_HUMAN

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0002522 leukocyte migration involved in immune response
GO:0002758 innate immune response-activating signal transduction
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007498 mesoderm development
GO:0008284 positive regulation of cell population proliferation
GO:0008360 regulation of cell shape
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0030133 transport vesicle
GO:0030154 cell differentiation
GO:0030838 positive regulation of actin filament polymerization
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042995 cell projection
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043299 leukocyte degranulation
GO:0045087 innate immune response
GO:0045728 respiratory burst after phagocytosis
GO:0046777 protein autophosphorylation
GO:0050690 regulation of defense response to virus by virus
GO:0050727 regulation of inflammatory response
GO:0050764 regulation of phagocytosis
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0071801 regulation of podosome assembly
GO:2000251 positive regulation of actin cytoskeleton reorganization

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HCKMbpBioGRID, MINT18067320 details
HCKCblIntAct10092522 details