Entity Details

Primary name HLA-C
Entity type gene
Source Source Link

Details

PrimaryID3107
RefseqGeneNG_029422
SymbolHLA-C
Namemajor histocompatibility complex, class I, C
Chromosome6
Location6p21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-10-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHLAC_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002250 adaptive immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0009986 cell surface
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0016032 viral process
GO:0030667 secretory granule membrane
GO:0030670 phagocytic vesicle membrane
GO:0031901 early endosome membrane
GO:0042605 peptide antigen binding
GO:0042612 MHC class I protein complex
GO:0043312 neutrophil degranulation
GO:0046977 TAP binding
GO:0050776 regulation of immune response
GO:0055038 recycling endosome membrane
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0070062 extracellular exosome
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
HLA-CTuba3aBioGRID, IntAct26496610 details
HLA-CTuba3bIntAct26496610 details
HLA-CBmpr1aBioGRID, IntAct26496610 details
HLA-CRab5cBioGRID, IntAct26496610 details
HLA-CCalml3BioGRID, IntAct26496610 details
HLA-CPtpn2BioGRID, IntAct26496610 details
HLA-CTgfbr1BioGRID, IntAct26496610 details