Entity Details

Primary name APC
Entity type gene
Source Source Link

Details

PrimaryID324
RefseqGeneNG_008481
SymbolAPC
NameAPC regulator of WNT signaling pathway
Chromosome5
Location5q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-29
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsAPC_HUMAN

GO terms

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GOName
GO:0000281 mitotic cytokinesis
GO:0000776 kinetochore
GO:0001708 cell fate specification
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0006974 cellular response to DNA damage stimulus
GO:0007026 negative regulation of microtubule depolymerization
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007155 cell adhesion
GO:0007389 pattern specification process
GO:0007399 nervous system development
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0008285 negative regulation of cell population proliferation
GO:0008286 insulin receptor signaling pathway
GO:0010942 positive regulation of cell death
GO:0016055 Wnt signaling pathway
GO:0016328 lateral plasma membrane
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0016579 protein deubiquitination
GO:0019887 protein kinase regulator activity
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030335 positive regulation of cell migration
GO:0030877 beta-catenin destruction complex
GO:0031274 positive regulation of pseudopodium assembly
GO:0031625 ubiquitin protein ligase binding
GO:0032587 ruffle membrane
GO:0032886 regulation of microtubule-based process
GO:0043065 positive regulation of apoptotic process
GO:0045295 gamma-catenin binding
GO:0045595 regulation of cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048471 perinuclear region of cytoplasm
GO:0051010 microtubule plus-end binding
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0065003 protein-containing complex assembly
GO:0070830 bicellular tight junction assembly
GO:0070840 dynein complex binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1904781 positive regulation of protein localization to centrosome
GO:1904885 beta-catenin destruction complex assembly
GO:1904886 beta-catenin destruction complex disassembly
GO:1990909 Wnt signalosome
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

18 interactions