Entity Details

Primary name AIRE
Entity type gene
Source Source Link

Details

PrimaryID326
RefseqGeneNG_009556
SymbolAIRE
Nameautoimmune regulator
Chromosome21
Location21q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsAIRE_HUMAN

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0002458 peripheral T cell tolerance induction
GO:0002509 central tolerance induction to self antigen
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006955 immune response
GO:0006959 humoral immune response
GO:0008270 zinc ion binding
GO:0016604 nuclear body
GO:0032722 positive regulation of chemokine production
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0045060 negative thymic T cell selection
GO:0045182 translation regulator activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0097536 thymus epithelium morphogenesis
GO:2000410 regulation of thymocyte migration

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AIRENaspIntAct20085707 details
AIREMybbp1aIntAct20085707 details