Entity Details

Primary name HSF1
Entity type gene
Source Source Link

Details

PrimaryID3297
RefseqGene
SymbolHSF1
Nameheat shock transcription factor 1
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsHSF1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000776 kinetochore
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006397 mRNA processing
GO:0006952 defense response
GO:0007584 response to nutrient
GO:0008284 positive regulation of cell population proliferation
GO:0009299 mRNA transcription
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0014823 response to activity
GO:0016032 viral process
GO:0016605 PML body
GO:0019901 protein kinase binding
GO:0031072 heat shock protein binding
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031490 chromatin DNA binding
GO:0033574 response to testosterone
GO:0034605 cellular response to heat
GO:0034620 cellular response to unfolded protein
GO:0034622 cellular protein-containing complex assembly
GO:0035865 cellular response to potassium ion
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043621 protein self-association
GO:0045651 positive regulation of macrophage differentiation
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051028 mRNA transport
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051879 Hsp90 protein binding
GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress
GO:0061770 translation elongation factor binding
GO:0070301 cellular response to hydrogen peroxide
GO:0071222 cellular response to lipopolysaccharide
GO:0071276 cellular response to cadmium ion
GO:0071280 cellular response to copper ion
GO:0071392 cellular response to estradiol stimulus
GO:0071480 cellular response to gamma radiation
GO:0072738 cellular response to diamide
GO:0090084 negative regulation of inclusion body assembly
GO:0090261 positive regulation of inclusion body assembly
GO:0097165 nuclear stress granule
GO:0097431 mitotic spindle pole
GO:0097677 STAT family protein binding
GO:0098847 sequence-specific single stranded DNA binding
GO:0101031 chaperone complex
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900034 regulation of cellular response to heat
GO:1900365 positive regulation of mRNA polyadenylation
GO:1901215 negative regulation of neuron death
GO:1902512 positive regulation of apoptotic DNA fragmentation
GO:1903936 cellular response to sodium arsenite
GO:1904385 cellular response to angiotensin
GO:1904528 positive regulation of microtubule binding
GO:1904843 cellular response to nitroglycerin
GO:1904845 cellular response to L-glutamine
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:1990904 ribonucleoprotein complex
GO:1990910 response to hypobaric hypoxia
GO:1990911 response to psychosocial stress
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HSF1ZwintBioGRID, IntAct20360068 details