Entity Details

Primary name XIAP
Entity type gene
Source Source Link

Details

PrimaryID331
RefseqGeneNG_007264
SymbolXIAP
NameX-linked inhibitor of apoptosis
ChromosomeX
LocationXq25
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-15
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsXIAP_HUMAN

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0006974 cellular response to DNA damage stimulus
GO:0016055 Wnt signaling pathway
GO:0030510 regulation of BMP signaling pathway
GO:0031398 positive regulation of protein ubiquitination
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045088 regulation of innate immune response
GO:0046872 metal ion binding
GO:0050727 regulation of inflammatory response
GO:0051402 neuron apoptotic process
GO:0051726 regulation of cell cycle
GO:0055070 copper ion homeostasis
GO:0061630 ubiquitin protein ligase activity
GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1902530 positive regulation of protein linear polyubiquitination
GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
XIAPNotch1BioGRID17318174 details
XIAPHtra2IntAct11604410 details
XIAPBex3BioGRID15178455 details
XIAPDiabloBioGRID11606597 details
XIAPRanbp2BioGRID, IntAct26496610 details
XIAPCnot2BioGRID, IntAct26496610 details
XIAPZbtb48BioGRID, IntAct26496610 details
XIAPSumo3BioGRID, IntAct26496610 details
XIAPRnf183BioGRID31732153 details