Entity Details

Primary name IDH2
Entity type gene
Source Source Link

Details

PrimaryID3418
RefseqGeneNG_023302
SymbolIDH2
Nameisocitrate dehydrogenase (NADP(+)) 2
Chromosome15
Location15q26.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-11-02
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsIDHP_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0005975 carbohydrate metabolic process
GO:0006097 glyoxylate cycle
GO:0006099 tricarboxylic acid cycle
GO:0006102 isocitrate metabolic process
GO:0006103 2-oxoglutarate metabolic process
GO:0006739 NADP metabolic process
GO:0006741 NADP biosynthetic process
GO:0051287 NAD binding
GO:0060253 negative regulation of glial cell proliferation
GO:0070062 extracellular exosome
GO:1903976 negative regulation of glial cell migration
GO:1904465 negative regulation of matrix metallopeptidase secretion

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IDH2Mad2l1BioGRID, IntAct26496610 details