Entity Details

Primary name IGF1R
Entity type gene
Source Source Link

Details

PrimaryID3480
RefseqGeneNG_009492
SymbolIGF1R
Nameinsulin like growth factor 1 receptor
Chromosome15
Location15q26.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsIGF1R_HUMAN

GO terms

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GOName
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005009 insulin-activated receptor activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005198 structural molecule activity
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005899 insulin receptor complex
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0008284 positive regulation of cell population proliferation
GO:0008286 insulin receptor signaling pathway
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0016032 viral process
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0031994 insulin-like growth factor I binding
GO:0033674 positive regulation of kinase activity
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043243 positive regulation of protein-containing complex disassembly
GO:0043410 positive regulation of MAPK cascade
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding
GO:0045056 transcytosis
GO:0046328 regulation of JNK cascade
GO:0046777 protein autophosphorylation
GO:0048009 insulin-like growth factor receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0051389 obsolete inactivation of MAPKK activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0071333 cellular response to glucose stimulus
GO:0097062 dendritic spine maintenance
GO:0097242 amyloid-beta clearance
GO:0120162 positive regulation of cold-induced thermogenesis
GO:0140318 protein transporter activity
GO:1902911 protein kinase complex
GO:1904646 cellular response to amyloid-beta

Diseases

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Interactions

8 interactions