Entity Details

Primary name IGFBP3
Entity type gene
Source Source Link

Details

PrimaryID3486
RefseqGeneNG_011508
SymbolIGFBP3
Nameinsulin like growth factor binding protein 3
Chromosome7
Location7p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-12-04
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsIBP3_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0001933 negative regulation of protein phosphorylation
GO:0001968 fibronectin binding
GO:0005520 insulin-like growth factor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005788 endoplasmic reticulum lumen
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0008160 protein tyrosine phosphatase activator activity
GO:0008285 negative regulation of cell population proliferation
GO:0009968 negative regulation of signal transduction
GO:0010906 regulation of glucose metabolic process
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016942 insulin-like growth factor binding protein complex
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0042567 insulin-like growth factor ternary complex
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043410 positive regulation of MAPK cascade
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044342 type B pancreatic cell proliferation
GO:0045663 positive regulation of myoblast differentiation
GO:0046872 metal ion binding
GO:0048662 negative regulation of smooth muscle cell proliferation

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IGFBP3Ltbp1BioGRID12962157 details
IGFBP3Igf2BioGRID12962157 details