Entity Details

Primary name RBPJ
Entity type gene
Source Source Link

Details

PrimaryID3516
RefseqGeneNG_030343
SymbolRBPJ
Namerecombination signal binding protein for immunoglobulin kappa J region
Chromosome4
Location4p15.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-10-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSUH_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001756 somitogenesis
GO:0001837 epithelial to mesenchymal transition
GO:0001974 blood vessel remodeling
GO:0002193 MAML1-RBP-Jkappa- ICN1 complex
GO:0002437 inflammatory response to antigenic stimulus
GO:0003139 secondary heart field specification
GO:0003151 outflow tract morphogenesis
GO:0003160 endocardium morphogenesis
GO:0003176 aortic valve development
GO:0003177 pulmonary valve development
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003214 cardiac left ventricle morphogenesis
GO:0003222 ventricular trabecula myocardium morphogenesis
GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006959 humoral immune response
GO:0007219 Notch signaling pathway
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009912 auditory receptor cell fate commitment
GO:0009957 epidermal cell fate specification
GO:0010628 positive regulation of gene expression
GO:0017053 transcription repressor complex
GO:0021983 pituitary gland development
GO:0030183 B cell differentiation
GO:0030216 keratinocyte differentiation
GO:0030279 negative regulation of ossification
GO:0030513 positive regulation of BMP signaling pathway
GO:0035019 somatic stem cell population maintenance
GO:0035912 dorsal aorta morphogenesis
GO:0036302 atrioventricular canal development
GO:0042742 defense response to bacterium
GO:0043011 myeloid dendritic cell differentiation
GO:0043565 sequence-specific DNA binding
GO:0045596 negative regulation of cell differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0047485 protein N-terminus binding
GO:0048505 regulation of timing of cell differentiation
GO:0048733 sebaceous gland development
GO:0048820 hair follicle maturation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060412 ventricular septum morphogenesis
GO:0060486 club cell differentiation
GO:0060716 labyrinthine layer blood vessel development
GO:0060844 arterial endothelial cell fate commitment
GO:0061314 Notch signaling involved in heart development
GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0072554 blood vessel lumenization
GO:0097101 blood vessel endothelial cell fate specification
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1901186 positive regulation of ERBB signaling pathway
GO:1901189 positive regulation of ephrin receptor signaling pathway
GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RBPJNotch1BioGRID, MINT19503073 21102556 details
RBPJFhl1MINT15710417 details
RBPJXpo1IntAct26673895 details