Entity Details

Primary name IKBKB
Entity type gene
Source Source Link

Details

PrimaryID3551
RefseqGeneNG_041793
SymbolIKBKB
Nameinhibitor of nuclear factor kappa B kinase subunit beta
Chromosome8
Location8p11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsIKKB_HUMAN

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006954 inflammatory response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0008384 IkappaB kinase activity
GO:0008385 IkappaB kinase complex
GO:0009615 response to virus
GO:0009898 cytoplasmic side of plasma membrane
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0016032 viral process
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030866 cortical actin cytoskeleton organization
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035509 negative regulation of myosin-light-chain-phosphatase activity
GO:0035631 CD40 receptor complex
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042325 regulation of phosphorylation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051403 stress-activated MAPK cascade
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071356 cellular response to tumor necrosis factor
GO:0072659 protein localization to plasma membrane
GO:0097110 scaffold protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903140 regulation of establishment of endothelial barrier
GO:1903347 negative regulation of bicellular tight junction assembly
GO:1990459 transferrin receptor binding

Diseases

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Interactions

8 interactions