Entity Details

Primary name IL6ST
Entity type gene
Source Source Link

Details

PrimaryID3572
RefseqGene
SymbolIL6ST
Nameinterleukin 6 cytokine family signal transducer
Chromosome5
Location5q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIL6RB_HUMAN

GO terms

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GOName
GO:0002675 positive regulation of acute inflammatory response
GO:0002821 positive regulation of adaptive immune response
GO:0004896 cytokine receptor activity
GO:0004897 ciliary neurotrophic factor receptor activity
GO:0004921 interleukin-11 receptor activity
GO:0005127 ciliary neurotrophic factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005896 interleukin-6 receptor complex
GO:0005900 oncostatin-M receptor complex
GO:0005977 glycogen metabolic process
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0016020 membrane
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0019838 growth factor binding
GO:0019955 cytokine binding
GO:0019970 interleukin-11 binding
GO:0030425 dendrite
GO:0034097 response to cytokine
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043235 receptor complex
GO:0045509 interleukin-27 receptor activity
GO:0045669 positive regulation of osteoblast differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0048711 positive regulation of astrocyte differentiation
GO:0048861 leukemia inhibitory factor signaling pathway
GO:0060576 intestinal epithelial cell development
GO:0070062 extracellular exosome
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070110 ciliary neurotrophic factor receptor complex
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IL6STStat3IntAct, MINT10982829 8662591 details
IL6STLmo4BioGRID15677447 details